It's not Vista that's really the problem. Vista was distributed with .NET 2.0 as the base .NET framework.
You need .NET 1.1 for the CastleLink software to work.
Install the Microsoft .NET Framework Version 1.1 Redistributable Package from here:
http://www.microsoft.com/downloads/d...displaylang=en
It fixed all the problem i was having initially wth Vista and Castle software. I don't have a Vista64 pc, so I do hope it resolve Vista64 problems the same way it resolved Vista32 problems.