The big problem would be hooking it up to some kind of wifi, 3g, or cell phone network to transfer information to it. That would requre some kind of decice that plugs into the esc, or possibly a small component on the esc itself. It would probably have to have a screen/buttons so you could connect to a network. If you go that far you might as well just have a programming card..
However, the Idea is still badass. Maybe a wire could connect the esc to a iphone/itouch?