Nope, that's not going to work I'm afraid. In a nutshell, sensorless brushless ESCs use back-EMF pulses from the motor in order to know what position the rotor's in, so that they can drive the motor. Trying to run two motors on one ESC would result in two "sets" of back-EMF pulses, which would totally confuse the ESC and probably end up frying it. In theory it's possible if the motors were completely synchronised (identical KV and rotor start position), but simply getting hold of two motors with identical KV is nigh impossible.
In short, two motors on one ESC isn't going to happen I'm afraid. Twin VXL systems work, but they're an inefficient way of doing things; the two motors will always be fighting each other slightly because they're running on the same spur, and it's also a heavier solution. Plus, with two motors, you'll always get lower total efficiency than with one high-quality motor...and the VXL motors are already run hot. Lastly, it's more expensive.
Besides, two motors are completely unnecessary; one large motor can easily provide enough gumption. It might not look perfectly symmetrical, or as "cool" as two motors do, but you'll enjoy the lower cost, higher efficiency and greater simplicity of just one motor. Efficiency is *everything* in a brushless setup.
Edit: Just saw Jerry's post. RiverMaxx, the SuperDuty XR speedo that Jerry's talking about is a brushed-only controller. You can run twin brushed motors easily, but not brushless. I thought I'd try to avoid any confusion there.