4s and 100% endpoint is certainly more efficient than 5s and 75% endpoint. If you use a pinion gear 4/5 the size with 5s and 100% endpoint you'll probably get even more runtime.
Check out my custom converted 8ight:
Sub 7lb, lowest CG of any 1/8 buggy
What brand/type clutch and bell do you use? Is it the traxxas style or a std 1/8 scale clutch? You should be able to go down to a 12t bell, and go back up with the throttle epa...
Also remembered that losi brought out a 50t spur, that would help lower the gearing too...